News Updates

Studies Support Shortened, 8-Week HCV Treatment

Evidence supporting the FDA-approved option to shorten treatment of hepatitis C virus (HCV) genotypes 1 and 3 infection without cirrhosis with glecaprevir-pibrentasvir (Mavyret) from 12 weeks to 8 was drawn from two large multicenter trials involving over 1200 patients.

Analysis of data from the phase 3, open-label trials comparing 8 and 12-week regimens was recently consolidated in a report published by Stefan Zeuzem, MD, Professor of Medicine and Chief, Department of Medicine I, Goethe University Hospital, Frankfurt, Germany and colleagues.

“Although the current standard-of-care treatments for patients without cirrhosis who are infected with HCV genotype 1 or genotype 3 result in high rates of sustained virologic response (SVR), patients could benefit from shorter-duration treatment options that maintain high efficacy irrespective of HCV genotype,” Zeuzem and colleagues noted.

The ENDURANCE-1 trial evaluated the efficacy and safety of the fixed dose combination of glecaprevir-pibrentasvir (GLE-PIB) in HCV genotype 1-infected patients, including those with human immunodeficiency virus type 1 (HIV-1) co-infection. Patients were randomized in a 1:1 ratio to receive GLE-PIB for either 8 or 12 weeks.

The ENDURANCE-3 trial compared efficacy and safety of GLE-PIB to treatment with sofosbuvir (Sovaldi) dosed with daclatasvir (Daklinza) in treatment-naive patients with genotype 3 infection. Initially, patients were randomized in a 2:1 ratio to receive either GLE-PIB (3 tablets yielding 300mg glecaprevir and 120mg pibrentasvir) or the combination of 400mg of sofosbuvir with 60mg daclatasvir daily for 12 weeks. After the availability of preliminary data supporting the efficacy of an 8-week regimen, the protocol was amended to include a third group for 8 weeks of treatment with GLE-PIB.

“Until recently, there were no approved treatment regimens with a duration of less than 12 weeks for patients with HCV genotype 3 infection,” said Zeuzem and colleagues, “and 8-week treatment options for patients with genotype 1 infection were limited according to virus subtype, treatment history, fibrosis stage, or baseline viral load.”

Zeuzem and colleagues reported that the SVR at 12 weeks was 99.1% among genotype 1-infected patients receiving 8 weeks of GLE-PIB, compared with 99.7% treated for 12 weeks. In patients with genotype-3 infection treated for 12 weeks, 95% receiving GLE-PIB and 97% receiving sofosbuvir/daclatasvir attained SVR. Ninety-five percent of the patients with genotype 3 infection treated with 8 weeks of GLE-PIB also attained SVR measured at 12 weeks.


Newer drugs make hepatitis C-positive kidneys safe for transplant

People who received kidneys from donors infected with hepatitis C did not become ill with the virus, thanks to treatment with newer drugs that can cure the disease, a small study reports.

Ten patients not previously infected with hepatitis C took doses of powerful antiviral medications before and after receiving the transplants. None of the patients developed chronic infections, researchers report online March 6 in the Annals of Internal Medicine. The finding could help make more kidneys available for transplants.

“If this increases access to transplantation, then this is a great benefit,” says Jay Fishman, a transplant infectious disease specialist at Massachusetts General Hospital in Boston.

As of January 2016, more than 100,000 people in the United States were awaiting transplants, according to the National Kidney Foundation. In many areas, patients can linger on waiting lists for more than five years. In 2014, there were about 17,000 kidney transplants in the country, and nearly 4,800 people died while waiting.

Traditionally, organs from donors with hepatitis C were offered to recipients already infected with the disease, because the virus could be transmitted during a transplant. And one of the main drugs previously used to treat the infectious liver disease was not very effective and had many side effects, including the possibility of transplant rejection. But in the last several years, more effective drugs, called direct-acting antivirals, have been approved for use. These drugs cure hepatitis C in more than 95 percent of patients.

At the same time, more hepatitis C-positive organs have become available. The increase is likely due to rising numbers of overdose deaths from opioids (SN: 6/10/17, p. 22), says Christine Durand, a transplant infectious disease specialist at Johns Hopkins School of Medicine.


Lenalid (Generic of Revlimid)

Lenalidomide is to improve the survival and quality of life of the cancer patients.

Packing of Lenalid-
Lenalid is accessible as 5mg, 10mg, 15mg & 25mg (30 tablets/bottle).

The Indian Pharma is one of the largest online consultancy company based in Delhi-NCR (India). We connect the patients across the globe to validated pharmaceutical distributors in India.

We provide the Lenalid (Generic of Revlimid) at the best price in India and Every week we have been serving many patients from various countries in Eastern and Southeastern Europe and Brazil, Venezuela & SE Asia including China and South East Asia.

You can Buy anti-cancer drugs and their generics from our Indian generic which is one of the best online consulting company in Delhi, India. who easily provides not only anti-cancer medicines but also offer the all types of medicines at cheapest and affordable prices at our website- and also contact through phone/WhatsApp and Mail- +91 8130290915 ,

Myhep LVIR is the combination Ledipasvir/Sofosbuvir

Mylan Pharma, has launched Ledipasvir 90 mg/Sofosbuvir 400 mg tablets under the brand name MyHep LVIR™ in India.

Dosage Information-
• The product is a single-tablet regimen and requires a treatment of just 12 weeks.
• Prescribed for 12 weeks for genotypes 1, 2 and 3 while 24 weeks for genotype 4.

For Purchase Myhep LVIR at best price than you can contact on below details,

You can go throught our wesite-

Velpanat (Velpatasvir and Sofosbuvir)

Velpanat is the combination medicine of Velpatasvir and Sofosbuvir which is manufactured by NATCO Pharma and available as 400 mg Sofosbuvir and 100 mg Velpatasvir as 28 Tablets in one bottle and it is used in the treatment of Chronic Hepatitis C.

We can help patients in accessing/importing VELPANAT at best discount, unapproved in their home country against a Valid prescription.

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HepBest For Hepatitis B

According to WHO more than 2 billion people worldwide are contaminated with Hepatitis B Virus (HBV) and 240 million people have chronic liver Infection.

Mylan Pharmaceutical launched HepBest 25 mg (Tenofovir alafenamide), this is the first drug in eight years to be approved for HBV in India.
HepBest is the prescription drug used to treat Chronic Hepatitis B Virus in Adults with stable liver Disease. Symptoms of a hepatitis B Infection may include: Tiredness/Fatigue, Joint Pain, Stomach Pain, Fever, Vomiting and Nausea, Loss of Appetite, Jaundice (Yellowish eyes and skin), light colored Stools/Dark Urine.

You must take HepBest exactly how your doctor tells you. Generally, take one small tablets once a day with food. Do not stop taking HepBest unless your doctor tells you to. If you stop taking your medicine, your HBV infection could get worse (flare-up).

If you are pregnant or plan to become pregnant. It is not known if HepBest will harm your unborn baby. Tell your healthcare provider if you become pregnant during treatment. If you are breastfeeding or plan to breastfeed. Talk with your healthcare provider to feed your baby. Do not start any new treatment or medicine without telling your healthcare provider.

Possible side effect of HepBest may include: New or worse kidney problem Including Kidney Failure, too much lactic acid in your blood (Tell your healthcare if you get these symptoms: weakness or more tired than usual, muscle pain, being short of breath or fast breath, stomach pain, nausea and vomiting, cold or blue hands and feet, feel dizzy or lightheaded, or a fast or abnormal heartbeat), Severe liver problems.

The most common side effect may Include: Headache, Stomach Pain, Tiredness, Cough, Nausea, Back Pain.

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Hepatitis C Treatment

What is Hepatitis C Virus?

Hepatitis C is an Infectious disease caused by Hepatits C Virus that infects the liver. During the initial infection people often have mild or no indications.Over many years however, it often leads to liver illness and cirrhosis. in some cases people with cirrhosis will develop complications such as liver faliure, liver cancer.

Hepatitis C virus is spread through contact with the blood of an infected person. Hepatitis C can be either “acute” or “chronic.”

Acute HCV infection is a short-term illness that occurs 15 % of cases. Symptoms includes a decreased appetite,weight loss, fatigue, nausea, muscle pains and joint pains, acute liver failure result.

Chronic Hepatitis C virus infection is a long-term illness that occurs 80% of cases. Hepatitis C virus infection can last a lifetime and cause serious liver problems, including cirrhosis or liver cancer.

How to get access Hepatitis C medications?

The Indian Pharma will help you to provide HCV medications by connecting Patients, Pharmacies and Retail stores through approved supplier, exporter and distributor of Generic medications.

In India HCV medications is marketed by diffrent Trade Name/Brand Name

The Innovator brand is available by International Trade Name/ Brand Name.

Patients, Pharmacies and Retail stores of generic medications can contact us by filling up the query form for further details relating to Generic medications, Innovator Brands and Biosimilar medical products.

Delivery of Hepatitis C medications

The Indian Pharma ( helps patient in connecting to the genuine pharmaceutical supplier to help access genuine medicine/ pharmaceutical drug (prescription drug, prescription medication or prescription medicine) that legally requires a medical prescription to be dispensed in following countries as per the customer’s prescribed medication and applicable regulatory approval.